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Protein Structural Analysis: Binding Sites to Distant Homologs
Description:
This course covers how to visualize and annotate 3D protein structures using NCBI's Cn3D program, identify conserved domain(s) and ligand binding sites in a protein, search for other proteins containing similar domain(s), explore a 3D modeling template for the query protein and find distant sequence homologs that may not be identified by BLAST.
To register, please visit the Registration Page.
Webpage Modified: October 14, 2009
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Formats for Training:
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Class
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Class
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Dates |
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2009/12/03
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1.30PM-3.30PM
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NIH Library Training Room, First Floor --Registration Page
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Hands-on. Free. NIH staff only. For more information call 301-496-1080
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Objectives:
- To visualize and annotate 3D protein structures using Cn3D, a free helper application for your web browser that allows you to view 3-dimensional structures
- To identify the conserved domain(s) present in the query protein and features such as ligand binding sites
- To search for other proteins containing similar domain(s)
- To explore 3D modeling template for the query protein
- To obtain distant sequence homologs that may not be identified by BLAST
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Who Should Attend:
Any NIH staff member with an interest in the topic
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Useful Handouts/Links:
This class is based on one of the mini-courses developed by the instructor Dr. Medha Bhagwat while working at NCBI
NCBI Mini-Courses
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